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“Others, especially deep-seated plexiform neurofibromas, may not be amenable to surgery.” The lack of effective treatment options especially for plexiform neurofibromas and MPNSTs is the main driving force behind the NF1 therapeutic pipeline — there are currently over 25 experimental drugs for neurofibromatosis in different stages of development
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Comput Methods Programs Biomed 28(3):157-70, 1989
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