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In KEYNOTE-426, patients with previously untreated metastatic RCC were treated with either pembrolizumab (anti-PD-1) and axitinib (VEGFR1, 2, and 3 inhibitor) combination therapy or sunitinib monotherapy, and significantly increased progression-free survival (PFS) was demonstrated in the combination group compared with the sunitinib group 93
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doi: 10.1111/j.1742-7843.2006.00015.x
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