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Elucidation of protective efficacy of Pentahydroxy flavone isolated from Madhuca indica against arsenite-induced cardiomyopathy: Role of Nrf-2, PPAR-γ, c-fos and c-jun
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1 Introduction With an aging global population, it is estimated that 2.2 billion people worldwide are suffering from visual dysfunction, which severely impedes the individual’s quality of life and poses threats to public health ( Ferroptosis, a term initially coined by Dixon in 2012, is a distinctive form of RCD featured by the iron-dependent lethal aggregation of lipid peroxides located at the cell membrane ( Figure 1 )
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