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The thioredoxin system is composed of Trx proteins and Trx reductases (TrxR), in which the reduced form of Trx proteins (Trx(SH) 2 ) are disulfide reductases as they contain dithiol groups in their highly conserved active site (-Cys-Gly-Pro-Cys-) (45, 46)
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A third randomized trial compared high-dose (10 mg/day) and low-dose (1.28 mg/day) vitamin B 6 in 60 pregnant women experiencing nausea and/or vomiting prior to the twelfth week of gestation (77)
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