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Overall, the evidence suggests that daily vitamin D supplementation of 2000–4000 IU combined with resistance or water-based aerobic training is likely effective for improving musculoskeletal and some metabolic outcomes, but the quantitative magnitude of benefit remains uncertain, and larger, longer-term, well-powered trials with rigorous adherence monitoring are needed to confirm these effects
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Conclusions This review explores the central role of Nrf2 as a key regulator of antioxidant defences required to maintain cellular redox balance
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