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Certain embodiments of the invention were virtually docked to NCA binding site of the mt-hNNMT monomer chain A [3ROD, PDB accession code] using the AutoDock Vina program
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That single added residue is the difference between it and the unmodified HGH Fragment 176-191, and it was introduced to improve stability and handling rather than to alter the activity, which makes the two a clean structural pair
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