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Methylsulfonylmethane (MSM) is a stable metabolite of dimethyl sulfoxide (DMSO), which has the characteristics of low toxicity, low residue, and low susceptibility to pathogen resistance [2–4]
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Pretreatment with vitamin E was shown to reduce lipid peroxidation levels (Lan and Jiang, 1997), but depletion of striatal DA was not attenuated by pretreatment (Gong et al., 1996) and only partial protection in MPTP-treated rodents (Perry et al., 1987)
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